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Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterised by intrahepatic lipid accumulation combined with the presence of at least one cardiometabolic risk factor (e.g., overweight/obesity, type 2 diabetes, hypertension, and dyslipidaemia)

The 4 mg to 8 mg jump is the hardest the GLP-1 and glucagon arms climb fastest there, while the GIP brake is already maxed out and adds nothing more